top of page

CBG vs CBD: Comparing Cannabinoids for Wellness

Updated: Jun 6, 2023


Cannabinoids have become increasingly recognized for their potential wellness benefits. Two prominent cannabinoids include cannabigerol (CBG) and cannabidiol (CBD), derived from cannabis plants but with differing properties and effects. We will compare CBG and CBD, discussing their similarities, potential health advantages, and many factors to consider when selecting between them.

What are cannabinoids?

Cannabinoids, chemical compounds found in cannabis plants, interact with our body's endocannabinoid system - which regulates various physiological functions - to manage various processes and physiological functions. CBG and CBD belong to this class of cannabinoids; however, their chemical structures and effects differ considerably depending on your unique body needs.

The differences between CBG and CBD

  1. Chemical Structure: CBG and CBD have distinctive chemical structures, each leading to distinct effects. CBG acts as the precursor cannabinoid from which other cannabinoids, including CBD, are synthesized; as a result, it typically appears in lower quantities in cannabis plants than its counterpart CBD.

  2. Effects on the Body: CBG and CBD interact with different receptors within the endocannabinoid system, typically CB1 and CB2 receptors, for pain modulation, inflammation reduction and mood regulation, respectively. At the same time, CBD's interaction is more complex, binding with multiple serotonin and vanilloid receptors.

  3. Potential Health Benefits: CBG and CBD have been investigated for their therapeutic potential. CBG shows promise in treating glaucoma, inflammatory bowel disease, and neurodegenerative conditions. At the same time, CBD is recognized for its analgesic, anxiolytic, and anti-inflammatory properties, commonly used to manage epilepsy and chronic pain conditions.

CBG and CBD: Similarities

  1. Interaction with the Endocannabinoid System: Both CBG and CBD interact with the body's natural endocannabinoid system through various mechanisms, modulating receptors, enzymes, and other components to maintain homeostasis within.

  2. Non-Intoxicating Properties: CBG and CBD offer non-intoxicating effects, unlike their cannabis-derived counterpart, Tetrahydrocannabinol (THC), making them more appealing to individuals looking for cannabinoids without unwanted psychoactive side effects.

  3. Therapeutic Potential of CBG and CBD: CBG and CBD have shown promise as therapeutic agents in medicine and wellness settings, according to studies that suggest they may assist with relieving symptoms associated with various conditions, such as anxiety, inflammation, pain, or seizures.

CBG vs CBD: Which is more effective?

Determining which cannabinoid is more effective depends on the targeted condition or symptom. Studies comparing CBG and CBD remain limited, yet some findings indicate that certain conditions may respond better to CBG while others could gain more from CBD.

For example, CBG has shown great promise in treating glaucoma due to its potential to decrease intraocular pressure. At the same time, CBD has earned recognition as an epilepsy and chronic pain treatment option. Additional research must be completed to ascertain which applications CBG and CBD serve best.

Understanding the entourage effect

The entourage effect refers to the interrelationships among cannabinoids, terpenes, and other compounds present in cannabis that work synergistically to create a greater therapeutic impact than when taken separately. Some experts suggest that consuming cannabinoids together, rather than isolating a single compound, could enhance their effectiveness.

Choosing between CBG and CBD products

When deciding between CBG and CBD products, several factors should be considered:

  1. Available Forms: CBG and CBD can be found in many forms, such as oils, capsules, topicals, and edibles. Each form offers unique advantages and considerations such as time to onset, bioavailability, and convenience.

  2. Considerations for Dosage: For optimal results, start slowly and slowly increase the dosage until the desired effects have been reached. It is wise to consult a healthcare professional or product guidelines when determining the ideal dose for an individual's specific needs.

  3. Legality and regulations: The legality of CBG and CBD products may vary depending on the jurisdiction. Understanding local regulations and sourcing products from reputable manufacturers ensures compliance and quality.

Are there any side effects or risks?

While CBG and CBD are generally well-tolerated, there are potential side effects and risks to be aware of:

  1. Common side effects: Mild side effects may include drowsiness, dry mouth, altered appetite, and gastrointestinal discomfort; these effects typically subside with continued use or dosage adjustments.

  2. Drug Interactions and Safety Precautions: CBG and CBD may interact with medications metabolized by liver enzymes, so it is recommended to seek professional advice before using cannabinoids, particularly if taking prescription medicines.


In summary, CBG and CBD cannabinoids possess distinct properties and potential wellness benefits. While CBG serves as the precursor of CBD, its main focus lies in therapeutic applications. The choice between CBG and CBD depends on individual needs and targeted conditions. Consulting with healthcare professionals and understanding product quality and regulations are essential for making informed decisions.


Are CBG and CBD the same thing?

CBG and CBD are different cannabinoids with distinct chemical structures and effects on the body.

Can CBG or CBD get you high?

No, neither CBG nor CBD produces a psychoactive high like THC.

Can CBG and CBD be used together?

Yes, using CBG and CBD together may have synergistic effects, potentially enhancing their therapeutic benefits.

Are CBG and CBD legal?

The legal status of CBG and CBD varies by jurisdiction. It is important to understand the local regulations before purchasing or using these cannabinoids.

What is the entourage effect?

The entourage effect refers to the combined therapeutic effects of cannabinoids, terpenes, and other compounds when used together instead of isolating individual compounds.

5 views0 comments


Rated 0 out of 5 stars.
No ratings yet

Add a rating

Do You Want A 10% Discount On Deliveries From Our Online Shop?

Thanks for subscribing!

bottom of page