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Appearance: Clear or white crystalline powder

Odor: No significant odor

Flavor: No significant flavor

Consistency: Fine-coarse powdered crystal

Solubility: Soluble with oils

Composition: 100% hemp extract by weight

Plant Parts Used in Oil: Whole plant

(flowers, leaves, stems, stalks, seeds)

CBD Isolate

PriceFrom $2.50
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  • According to The National Library of Medicine:

    Several studies suggest that THC and CBD may exert opposite actions on brain function and psychopathology [188], possibly in relation to the action of CBD as a potent CB1 receptor antagonist/inverse agonist [21] (see above). Several lines of preclinical work have shown that CBD reduces the effects of THC on several behavioral functions [189-191]. In line with these data, CBD has been found to reduce the anxiety and improve the sensation of well being induced by an acute, high THC dose in healthy volunteers [192].

    In contrast with these data, a number of studies have shown that CBD pretreatment potentiated the behavioral effects induced by THC [193-195]. These actions may signify the ability of CBD to inhibit cytochrome P450-mediated drug metabolism [196,197], which may increase THC blood and brain concentrations [193,195].

    Notably, the behavioral outcomes of CBD do not appear to be only due to potential pharmacodynamic/pharmacokynetic competition with THC; indeed, recent studies have shown that CBD exerts inherent anxiolytic effects, both in rodent models [157,198-201] and, more recently, in patients affected by social phobia [202,203]. The anxiolytic action of CBD may be linked to 5-HT1A receptor, but not through benzodiazepine receptors [204]. Of note, the anxiolytic action of CBD also appears to be bidirectional, as only low to moderate doses, but not high doses, have been associated with exert anxiolytic effects [200,205].

    The anxiolytic action of CBD do not appear to be mediated by benzodiazepine receptors [204], but rather by 5-HT1A serotonin receptors in the bed nucleus of the stria terminalis [206], a critical component of the amygdaloid complex involved in the regulation of stress response.

    Accordingly, CBD has been shown to reduce amygdalar responses to fearful stimuli [207]; this mechanism may be essential for the anxiolytic effects of this compound in social phobia [203]. Furthermore, CBD has been shown to elicit antipanic effects through the activation of 5-HT1A receptors in the dorsal periaqueductal gray, a critical area for the modulation of emotional reactivity to stress [208,209].


Everything You Need to Know


Yes, all of our products are accompanied with a third party lab test. We ensure that each batch is tested and safe for our consumers. View our COA's


We can accept credit card or crypto currencies at this time. For wholesale orders we accept Wire, ACH, Credit Card, Crypto, and checks.


A Certificate of Analysis (COA) is a laboratory report that provides data analysis about a specific product. A COA should be batch-specific and provide you with information about a product’s potency and cannabinoid profile.

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